Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858141 | 0.86 | GLRA1 (0.50) | PTPN1GLRA1MAPK1ALDH1A1TDP1 | |
| SCHEMBL18066369 | 0.84 | PTPN1 (0.72) | PTPN1GLRA1MAPK1BRD4ALDH1A1 | |
| SCHEMBL6200588 | 0.82 | PTPN1 (0.64) | PTPN1MAPTL3MBTL1MRGPRX4KDM4E | |
| SCHEMBL8896541 | 0.82 | PTPN1 (0.72) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL26908068 | 0.81 | GLRA1 (0.56) | PTPN1GLRA1BRD4ALDH1A1L3MBTL1 | |
| SCHEMBL14495325 | 0.81 | MAPK1 (0.57) | PTPN1MAPK1ALDH1A1PTGS2TDP1 | |
| SCHEMBL28078446 | 0.81 | GLRA1 (0.60) | GLRA1MAPK1ALDH1A1TDP1MAPT | |
| SCHEMBL6199219 | 0.81 | PTPN1 (0.63) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL6199847 | 0.81 | PTPN1 (0.63) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL6200654 | 0.81 | PTPN1 (0.63) | PTPN1MAPK1BRD4ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |