Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617567 | 0.87 | PTPN1 (0.61) | PTPN1NPC1MRGPRX4BRD4ALDH1A1 | |
| SCHEMBL6200588 | 0.84 | PTPN1 (0.64) | PTPN1NPC1MRGPRX4MAPTL3MBTL1 | |
| SCHEMBL8896541 | 0.84 | PTPN1 (0.72) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL18066381 | 0.83 | PTPN1 (0.76) | PTPN1NPC1MRGPRX4MAPK1BRD4 | |
| SCHEMBL6198469 | 0.83 | PTPN1 (0.63) | PTPN1MAPK1BRD4ALDH1A1PTGS2 | |
| SCHEMBL6199219 | 0.83 | PTPN1 (0.63) | PTPN1NPC1MRGPRX4MAPK1BRD4 | |
| SCHEMBL6200654 | 0.83 | PTPN1 (0.63) | PTPN1NPC1MRGPRX4MAPK1BRD4 | |
| SCHEMBL1766179 | 0.81 | MAPT (0.56) | NPC1MRGPRX4MAPK1KDM1AMAOB | |
| SCHEMBL6200447 | 0.81 | PTPN1 (0.60) | PTPN1MRGPRX4MAPK1BRD4ALDH1A1 | |
| SCHEMBL1115032 | 0.80 | PTPN1 (0.61) | PTPN1NPC1MRGPRX4MAPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |