⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543389 | 0.70 | CYP1A2 (0.32) | — | |
| Ethylene SCHEMBL28641046 | 0.67 | CYP1A2 (0.31) | — | |
| SCHEMBL6200554 | 0.65 | — | — | |
| SCHEMBL9752077 | 0.63 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL5779580 | 0.63 | — | — | |
| SCHEMBL2710911 | 0.63 | PTPN1 (0.40) | — | |
| SCHEMBL440013 | 0.62 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL8053864 | 0.61 | PTPN1 (0.42) | — | |
| SCHEMBL7053769 | 0.61 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL10438993 | 0.60 | SMN1; SMN2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | disclosed |
| EP-1042295-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| US-6093732-A | PREVENT HERPESVIRAL INFECTIONS, PARTICULARLY, HUMAN CYTOMEGALOVIRAL INFECTION | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1999032450-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0799052-A1 | NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF | Astra Aktiebolag (SE) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996016671-A1 | NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF | ASTRA AKTIEBOLAG (SE) | 1996-06-06 | — | — | WO | disclosed |