SCHEMBL1543389

SCHEMBL1543389

CCOC1OC(=O)CC(=O)O1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28641046 0.96 CYP1A2 (0.31) CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL5779580 0.74
SCHEMBL8195363 0.73 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL8521345 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL2070772 0.71
SCHEMBL15337522 0.70
SCHEMBL10438993 0.70 SMN1; SMN2 (0.38) CYP1A2SMN1; SMN2
SCHEMBL6200548 0.70
SCHEMBL321303 0.70 LMNA (0.32)
SCHEMBL13659733 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116200183-B High-efficiency variable-viscosity fracturing fluid for deep coal bed gas development and integrated construction method 四川申和新材料科技有限公司 2024-05-28 CN claimed
CN-114890945-B Method for synthesizing nadifloxacin intermediate 大连万福制药有限公司 2023-09-05 CN claimed
CN-116200183-A High-efficiency variable-viscosity fracturing fluid for deep coal bed gas development and integrated construction method 四川申和新材料科技有限公司 2023-06-02 CN claimed
EP-1513833-B1 NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2006-04-19 EP claimed
EP-1513833-A1 NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Les Laboratoires Servier (FR) 2005-03-16 EP claimed
WO-2004000834-A1 NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2003-12-31 WO claimed
EP-0267432-B1 ANTIBACTERIALLY ACTIVE PYRIDO-BENZOTHIAZINE DERIVATIVES WITH LONG TERM ACTION MEDIOLANUM FARMACEUTICI s.r.l. (IT) 1991-12-27 EP claimed
EP-0086723-B1 SUBSTITUTED PYRIMIDONES AND THEIR SALTS, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS, COMPOSITIONS CONTAINING THEM AND INTERMEDIATES OBTAINED ROUSSEL-UCLAF (FR) 1987-04-22 EP claimed
EP-0086723-A2 Substituted pyrimidones and their salts, their preparation, their application as medicaments, compositions containing them and intermediates obtained ROUSSEL-UCLAF (FR) 1983-08-24 EP claimed
CN-115433124-B Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline 常州佳德医药科技有限公司 2024-08-06 CN disclosed
CN-116200183-B High-efficiency variable-viscosity fracturing fluid for deep coal bed gas development and integrated construction method 四川申和新材料科技有限公司 2024-05-28 CN disclosed
US-20240109862-A1 SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH PFIZER INC. 2024-04-04 US disclosed
US-11925690-B2 Bifunctional molecules for targeting Rpn11 AMPHISTA THERAPEUTICS LIMITED (GB) 2024-03-12 US disclosed
WO-2024022487-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc (US) 2024-02-01 WO disclosed
EP-0090656-A1 Penicillins, a process for the preparation and compositions containing them BEECHAM GROUP PLC (GB) 1983-10-05 EP disclosed
US-4404205-A CARDIOTONIC AGENTS; ANGINA PECTORIS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1983-09-13 US disclosed
EP-0086723-A2 Substituted pyrimidones and their salts, their preparation, their application as medicaments, compositions containing them and intermediates obtained ROUSSEL-UCLAF (FR) 1983-08-24 EP disclosed
US-4367229-A 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1983-01-04 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed
US-3984548-A Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides RIKER LABORATORIES, INC. (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109862-A1 SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH GPR119, INSR, LYAR CYP1A2 3773/4885ALDH1A1 1427/4885SMN1; SMN2 1168/4885
US-11925690-B2 Bifunctional molecules for targeting Rpn11 RPN1, RPP30, UBQLN1 CYP1A2 4675/4885ALDH1A1 2199/4885SMN1; SMN2 1295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.