Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198701 | 0.94 | POLA1 (0.41) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6199591 | 0.92 | NR3C1 (0.38) | POLA1EGLN1NR3C1POLBCYP1A2 | |
| SCHEMBL6197282 | 0.87 | EGLN1 (0.41) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6199600 | 0.86 | EGLN1 (0.45) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6202008 | 0.85 | EGLN1 (0.41) | POLA1EGLN1NR3C1CYP1A2CYP2C9 | |
| SCHEMBL6198303 | 0.83 | EGLN1 (0.43) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6200817 | 0.83 | NR3C1 (0.49) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6198849 | 0.82 | EGLN1 (0.51) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6200824 | 0.82 | EGLN1 (0.48) | POLA1EGLN1NR3C1POLBMAOB | |
| SCHEMBL6682523 | 0.81 | EGLN1 (0.38) | POLA1EGLN1NR3C1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | disclosed |
| US-6093732-A | PREVENT HERPESVIRAL INFECTIONS, PARTICULARLY, HUMAN CYTOMEGALOVIRAL INFECTION | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-25 | — | — | US | disclosed |