⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940349 | 0.81 | DAO (0.31) | — | |
| SCHEMBL7809407 | 0.75 | — | — | |
| SCHEMBL771242 | 0.75 | PTGS2 (0.41) | — | |
| SCHEMBL28841090 | 0.75 | PTGS2 (0.41) | — | |
| SCHEMBL15709893 | 0.75 | PTGS2 (0.41) | — | |
| SCHEMBL17785186 | 0.75 | PTGS2 (0.41) | — | |
| SCHEMBL14839942 | 0.74 | PTGS2 (0.40) | — | |
| SCHEMBL21808122 | 0.73 | NR5A1 (0.40) | — | |
| SCHEMBL937881 | 0.71 | NPC1 (0.37) | — | |
| SCHEMBL3322195 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | disclosed |
| CN-1128790-C | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents | UPJOHN CO (US) | 2003-11-26 | — | — | CN | disclosed |
| CN-1281439-A | 4-hydroxyquinoline-3-carboxamide and hydrazide compounds as antiviral agents | UPJOHN CO (US) | 2001-01-24 | — | — | CN | disclosed |
| EP-1042295-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| US-6093732-A | PREVENT HERPESVIRAL INFECTIONS, PARTICULARLY, HUMAN CYTOMEGALOVIRAL INFECTION | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1999032450-A1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |