SCHEMBL620120

SCHEMBL620120

CCC(C)(O)C([SiH3])(C1CC1)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL621064 0.78
SCHEMBL8222929 0.75
SCHEMBL621687 0.74
SCHEMBL18086914 0.70
SCHEMBL458137 0.69
SCHEMBL28865480 0.68
SCHEMBL10454218 0.66 TSHR (0.46)
SCHEMBL2821815 0.66 TSHR (0.46)
SCHEMBL32688063 0.66 TSHR (0.46)
SCHEMBL10454220 0.66 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421873-B1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2014-07-02 EP claimed
US-8182781-B2 Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil GIVAUDAN S.A. (CH) 2012-05-22 US claimed
EP-2421873-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL Givaudan SA (CH) 2012-02-29 EP claimed
US-20120040879-A1 Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil GIVAUDAN SA (CH) 2012-02-16 US claimed
WO-2010121979-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2010-10-28 WO claimed
EP-2421873-B1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2014-07-02 EP disclosed
US-8182781-B2 Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil GIVAUDAN S.A. (CH) 2012-05-22 US disclosed
EP-2421873-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL Givaudan SA (CH) 2012-02-29 EP disclosed
US-20120040879-A1 Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil GIVAUDAN SA (CH) 2012-02-16 US disclosed
WO-2010121979-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2010-10-28 WO disclosed