⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620120 | 0.74 | — | — | |
| SCHEMBL621064 | 0.70 | — | — | |
| SCHEMBL12557497 | 0.69 | THRB (0.32) | — | |
| SCHEMBL8222431 | 0.69 | THRB (0.32) | — | |
| SCHEMBL8223094 | 0.69 | THRB (0.32) | — | |
| SCHEMBL11307245 | 0.67 | — | — | |
| SCHEMBL7526154 | 0.67 | LMNA (0.42) | — | |
| SCHEMBL456619 | 0.67 | — | — | |
| SCHEMBL31344344 | 0.67 | — | — | |
| SCHEMBL807045 | 0.65 | LMNA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421873-B1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2014-07-02 | — | — | EP | claimed |
| US-8182781-B2 | Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil | GIVAUDAN S.A. (CH) | 2012-05-22 | — | — | US | claimed |
| EP-2421873-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | Givaudan SA (CH) | 2012-02-29 | — | — | EP | claimed |
| US-20120040879-A1 | Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil | GIVAUDAN SA (CH) | 2012-02-16 | — | — | US | claimed |
| WO-2010121979-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2010-10-28 | — | — | WO | claimed |
| EP-2421873-B1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| US-8182781-B2 | Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil | GIVAUDAN S.A. (CH) | 2012-05-22 | — | — | US | disclosed |
| EP-2421873-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | Givaudan SA (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120040879-A1 | Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil | GIVAUDAN SA (CH) | 2012-02-16 | — | — | US | disclosed |
| WO-2010121979-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2010-10-28 | — | — | WO | disclosed |