Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599400 | 0.82 | HSD17B10 (0.56) | PTPN1SMN1; SMN2USP2CYP3A4MAPK1 | |
| SCHEMBL29043392 | 0.81 | PTPN1 (0.45) | PTPN1SMN1; SMN2USP2CYP3A4MAPK1 | |
| SCHEMBL15756386 | 0.79 | PTPN1 (0.44) | PTPN1SMN1; SMN2USP2CYP3A4MAPK1 | |
| SCHEMBL10683811 | 0.79 | USP2 (0.44) | PTPN1SMN1; SMN2USP2CYP3A4MAPK1 | |
| SCHEMBL11220923 | 0.78 | PLA2G2A (0.51) | SMN1; SMN2LMNAHSD17B10CA12CA1 | |
| SCHEMBL27986455 | 0.77 | CYP3A4 (0.49) | PTPN1SMN1; SMN2USP2CYP3A4MAPK1 | |
| SCHEMBL8154596 | 0.77 | CYP3A4 (0.53) | PTPN1SMN1; SMN2USP2CYP3A4MAPK1 | |
| SCHEMBL30522046 | 0.77 | KMT2A (0.56) | SMN1; SMN2LMNAHTTHSD17B10CA12 | |
| SCHEMBL3456256 | 0.77 | KMT2A (0.56) | SMN1; SMN2LMNAHTTHSD17B10CA12 | |
| SCHEMBL2847513 | 0.76 | MAPK8 (0.50) | CYP3A4CA2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329948-B2 | Method for the synthesis of substituted formylamines and substituted amines | BOBYLEV MIKHAIL (US) | 2012-12-11 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |