SCHEMBL6201529

SCHEMBL6201529

CN1C[CH]C(=O)N(C)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9020974 0.73
SCHEMBL1062964 0.72
SCHEMBL1825324 0.68
SCHEMBL6201675 0.67
SCHEMBL8773307 0.66 BRD4 (0.38) BRD4BRD2
SCHEMBL6196698 0.64
SCHEMBL12853520 0.62 GSK3A (0.36) BRD4BRD2GSK3AGSK3BMGLL
SCHEMBL17802440 0.62
SCHEMBL82607 0.62
SCHEMBL717518 0.60 BRD4 (0.43) BRD4BRD2GSK3AGSK3BMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165532-B1 ANTIBACTERIAL AGENTS VERNALIS OXFORD LTD (GB) 2005-01-12 EP disclosed
US-6503897-B1 N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2003-01-07 US disclosed