Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196782 | 0.87 | EGLN1 (0.42) | EGLN1NR3C1LMNAPOLA1CYP1A2 | |
| SCHEMBL6196787 | 0.87 | EGLN1 (0.42) | EGLN1NR3C1LMNAPOLA1CYP1A2 | |
| SCHEMBL6199464 | 0.87 | EGLN1 (0.44) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6201438 | 0.86 | EGLN1 (0.44) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6198781 | 0.85 | EGLN1 (0.45) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6202159 | 0.85 | EGLN1 (0.43) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6198169 | 0.84 | EGLN1 (0.49) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6199166 | 0.83 | LMNA (0.45) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6202257 | 0.82 | EGLN1 (0.42) | EGLN1NR3C1LMNAPTGER4PTGER2 | |
| SCHEMBL6201600 | 0.82 | EGLN1 (0.47) | EGLN1NR3C1LMNAPTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |