Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201666 | 1.00 | CTSK (0.40) | CTSKCA1CA7CA2TDP1 | |
| SCHEMBL6201206 | 0.73 | CA1 (0.43) | CTSKCA1CA7CA2CYP2D6 | |
| SCHEMBL3151434 | 0.73 | CA1 (0.43) | CTSKCA1CA7CA2CYP2D6 | |
| SCHEMBL6202245 | 0.73 | CA1 (0.43) | CTSKCA1CA7CA2CYP2D6 | |
| SCHEMBL18793620 | 0.72 | CA12 (0.42) | CTSKCA1CA7CA2CYP2D6 | |
| SCHEMBL31269564 | 0.71 | CTSK (0.44) | CTSKCA1CA7CA2CTSS | |
| SCHEMBL13050499 | 0.70 | ACE (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL13080563 | 0.70 | ACE (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7897117 | 0.70 | CA1 (0.41) | CTSKCA1CA7CA2CYP2D6 | |
| SCHEMBL12866689 | 0.68 | CA1 (0.46) | CTSKCA1CA7CA2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |