Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286181 | 0.91 | L3MBTL1 (0.61) | PDPK1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL23531267 | 0.86 | PDPK1 (0.61) | PDPK1KMT2AL3MBTL1TDP1NPSR1 | |
| SCHEMBL909083 | 0.82 | PDPK1 (0.57) | PDPK1KMT2AL3MBTL1TDP1NPSR1 | |
| SCHEMBL32689546 | 0.80 | PDPK1 (0.59) | PDPK1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL14602841 | 0.79 | PDPK1 (0.51) | PDPK1KMT2AATMNPC1MEN1 | |
| SCHEMBL28937529 | 0.79 | PDPK1 (0.51) | PDPK1KMT2AATMNPC1MEN1 | |
| SCHEMBL14602856 | 0.79 | PDPK1 (0.51) | PDPK1KMT2AATMNPC1MEN1 | |
| SCHEMBL2563387 | 0.79 | L3MBTL1 (0.63) | PDPK1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL12285825 | 0.78 | TDP1 (0.53) | PDPK1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL12286264 | 0.78 | L3MBTL1 (0.61) | PDPK1KMT2AL3MBTL1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |