Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182093 | 0.89 | EPHX2 (0.73) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL5948102 | 0.83 | EPHX2 (1.00) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL6204191 | 0.82 | EPHX2 (0.63) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL28242821 | 0.80 | EPHX2 (0.75) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL28242822 | 0.80 | EPHX2 (0.75) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL5529197 | 0.80 | EPHX2 (0.60) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL10722901 | 0.79 | EPHX2 (0.73) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL28241186 | 0.78 | L3MBTL1 (0.53) | EPHX2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL4638764 | 0.77 | EPHX2 (0.87) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL27790062 | 0.77 | EPHX2 (0.65) | EPHX2CYP2C9CYP2C19SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |