Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 16/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318924 | 0.91 | TBXA2R (0.57) | CYP24A1TBXA2RCYP19A1 | |
| SCHEMBL3945738 | 0.84 | CYP24A1 (0.63) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| SCHEMBL4412884 | 0.78 | CYP19A1 (0.60) | CYP24A1TBXA2RCYP19A1CYP17A1 | |
| SCHEMBL27721257 | 0.78 | CYP24A1 (0.56) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| SCHEMBL27721255 | 0.78 | CYP24A1 (0.56) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| SCHEMBL10862203 | 0.77 | CYP19A1 (0.50) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| SCHEMBL10857936 | 0.77 | CYP19A1 (0.50) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL28834589 | 0.77 | CYP24A1 (0.58) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| SCHEMBL27721268 | 0.77 | CYP24A1 (0.55) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 | |
| SCHEMBL27721270 | 0.77 | CYP24A1 (0.55) | CYP24A1TBXA2RCYP19A1CYP17A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |