Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 14/20 | 0.57 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.56 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201802 | 0.91 | CYP24A1 (0.62) | TBXA2RCYP24A1CYP19A1 | |
| SCHEMBL11239483 | 0.81 | CYP19A1 (0.51) | TBXA2RCYP24A1CYP27B1CYP19A1 | |
| SCHEMBL10247377 | 0.79 | CYP24A1 (0.54) | TBXA2RCYP24A1CYP19A1 | |
| SCHEMBL3945738 | 0.79 | CYP24A1 (0.63) | TBXA2RCYP24A1CYP19A1 | |
| Hydrochloric Acid SCHEMBL1776701 | 0.78 | CYP24A1 (0.53) | TBXA2RCYP24A1CYP19A1 | |
| SCHEMBL6202493 | 0.78 | MAPT (0.60) | CYP19A1 | |
| SCHEMBL10564669 | 0.76 | CYP19A1 (0.53) | CYP24A1CYP27B1CYP19A1 | |
| SCHEMBL11243475 | 0.74 | CYP19A1 (0.51) | TBXA2RCYP24A1CYP27B1CYP19A1 | |
| SCHEMBL11073325 | 0.74 | CYP24A1 (0.57) | TBXA2RCYP24A1CYP27B1CYP19A1 | |
| SCHEMBL9423713 | 0.73 | TBXA2R (1.00) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |