Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202062 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL1951853 | 0.77 | ANO1 (0.51) | ANO1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1907629 | 0.76 | ABL1 (0.56) | ANO1MEN1KMT2AMAPT | |
| SCHEMBL1953737 | 0.74 | ANO1 (0.58) | ANO1MEN1KMT2AMAPTATM | |
| SCHEMBL3629317 | 0.73 | ANO1 (0.71) | ANO1 | |
| SCHEMBL12271568 | 0.73 | ANO1 (0.58) | ANO1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8289730 | 0.73 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3626819 | 0.72 | MEN1 (0.71) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3628404 | 0.72 | MEN1 (0.70) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12271321 | 0.72 | ANO1 (0.55) | ANO1MEN1KMT2AMAPTPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509514-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003101979-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2003-12-11 | — | — | WO | claimed |