SCHEMBL6202076

SCHEMBL6202076

NC1CCCCCCCCCCNC1=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 5/20 0.44
MERTK Q12866 12/20 0.41
AXL P30530 1/20 0.40
FLT3 P36888 1/20 0.40
TYRO3 Q06418 1/20 0.40
HTT P42858 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6978411 1.00 CCR2 (0.44) CCR2MERTKAXLFLT3TYRO3
SCHEMBL15132456 1.00 CCR2 (0.44) CCR2MERTKAXLFLT3TYRO3
SCHEMBL1114446 0.98
SCHEMBL56745 0.98
SCHEMBL1927815 0.98
Hydrochloric Acid SCHEMBL1114699 0.95 CCR2 (0.41) CCR2MERTKAXLFLT3TYRO3
Hydrochloric Acid SCHEMBL1446953 0.95 CCR2 (0.41) CCR2MERTKAXLFLT3TYRO3
Hydrochloric Acid SCHEMBL3374187 0.95 CCR2 (0.41) CCR2MERTKAXLFLT3TYRO3
SCHEMBL11819356 0.95 CCR2 (0.41) CCR2MERTKAXLFLT3TYRO3
Hydrochloric Acid SCHEMBL11818708 0.95 CCR2 (0.41) CCR2MERTKAXLFLT3TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119012914-A Method for controlling parasitic plants 味之素株式会社 2024-11-22 CN disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
CN-103237832-B Method for producing monomer compositions and use thereof for producing polyamide molded parts BASF SE (DE) 2016-02-03 CN disclosed
CN-103857727-B Method for producing molded articles BASF SE (DE) 2016-01-20 CN disclosed
CN-103781820-B Process for producing molded article BASF SE (DE) 2016-01-20 CN disclosed
CN-103857727-A Method for producing molded articles BASF SE 2014-06-11 CN disclosed
CN-103781820-A Process for producing molded article BASF SE 2014-05-07 CN disclosed
CN-103237832-A Method for producing monomer compositions and use thereof for producing polyamide molded parts BASF SE 2013-08-07 CN disclosed
EP-1165532-B1 ANTIBACTERIAL AGENTS VERNALIS OXFORD LTD (GB) 2005-01-12 EP disclosed
US-6503897-B1 N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2003-01-07 US disclosed
WO-2000058294-A1 ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-10-05 WO disclosed
EP-0612324-A1 PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1994-08-31 EP disclosed
EP-0358305-B1 MERCAPTO-PHENYLALCANOYLAMINO ACID AMIDES, THEIR PREPARATION AND THEIR USE AS COLLAGENASE INHIBITORS BEECHAM GROUP PLC (GB) 1993-08-25 EP disclosed
US-5212163-A Phosphonate dipeptide or tripeptide derivatives as collagenase inhibitors for treatment of connective tissue disorders BEECHAM GROUP P.L.C. (GB) 1993-05-18 US disclosed
WO-1993009136-A1 PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1993-05-13 WO disclosed
US-5190937-A Collagenase Inhibitors BEECHAM GROUP P.L.C. (GB) 1993-03-02 US disclosed
US-5124322-A Antiarthritic agents BEECHAM GROUP P.L.C. (GB) 1992-06-23 US disclosed
EP-0438223-A1 N-(2-oxoazacycloalkyl) glutarylamide derivatives and their use as collagenase inhibitors Beecham Group p.l.c. (GB) 1991-07-24 EP disclosed
EP-0401963-A1 Phosphonopeptides with collagenase inhibiting activity Beecham Group p.l.c. (GB) 1990-12-12 EP disclosed
EP-0358305-A1 Mercapto-phenylalcanoylamino acid amides, their preparation and their use as collagenase inhibitors BEECHAM GROUP PLC (GB) 1990-03-14 EP disclosed