Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202848 | 0.85 | EGLN1 (0.36) | EGLN1NR3C1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6199883 | 0.81 | EGLN1 (0.37) | EGLN1LMNA | |
| SCHEMBL6220077 | 0.77 | EGLN1 (0.45) | EGLN1NR3C1SMN1; SMN2POLA1HPGD | |
| SCHEMBL6200217 | 0.77 | EGLN1 (0.45) | EGLN1NR3C1SMN1; SMN2POLA1HPGD | |
| SCHEMBL6201997 | 0.76 | EGLN1 (0.37) | EGLN1NR3C1POLA1HPGDCYP1A1 | |
| SCHEMBL6198849 | 0.75 | EGLN1 (0.51) | EGLN1NR3C1SMN1; SMN2POLA1HPGD | |
| SCHEMBL6200824 | 0.74 | EGLN1 (0.48) | EGLN1NR3C1SMN1; SMN2POLA1HPGD | |
| SCHEMBL6197455 | 0.74 | NR3C1 (0.44) | EGLN1NR3C1POLA1HPGDPOLB | |
| SCHEMBL6196605 | 0.73 | EGLN1 (0.47) | EGLN1NR3C1SMN1; SMN2POLA1HPGD | |
| SCHEMBL6194761 | 0.73 | POLA1 (0.54) | EGLN1NR3C1SMN1; SMN2POLA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | disclosed |
| US-6093732-A | PREVENT HERPESVIRAL INFECTIONS, PARTICULARLY, HUMAN CYTOMEGALOVIRAL INFECTION | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-25 | — | — | US | disclosed |