Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202318 | 1.00 | TSHR (0.35) | TSHRALDH1A1TRPV1ALOX12OXER1 | |
| SCHEMBL16103148 | 0.88 | ALOX12 (0.33) | TSHRALDH1A1TRPV1ALOX12OXER1 | |
| SCHEMBL16103147 | 0.88 | ALOX12 (0.33) | TSHRALDH1A1TRPV1ALOX12OXER1 | |
| SCHEMBL5610514 | 0.85 | — | — | |
| SCHEMBL1114072 | 0.85 | — | — | |
| SCHEMBL11064340 | 0.84 | PPARA (0.37) | TSHRALDH1A1TRPV1ALOX12OXER1 | |
| SCHEMBL11064344 | 0.84 | PPARA (0.37) | TSHRALDH1A1TRPV1ALOX12OXER1 | |
| SCHEMBL136668 | 0.79 | TSHR (0.41) | TSHRALDH1A1TRPV1EP300KAT2B | |
| SCHEMBL7752343 | 0.79 | PPARA (0.34) | — | |
| SCHEMBL1288145 | 0.79 | TSHR (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268457-A4 | REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT | LOCTITE CORP (US) | 2005-07-20 | — | — | EP | disclosed |
| EP-1268457-A1 | REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT | LOCTITE CORPORATION (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074798-A1 | REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT | LOCTITE CORPORATION (US) | 2001-10-11 | — | — | WO | disclosed |