Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201171 | 0.89 | EGLN1 (0.42) | CYP3A4LMNAMAPTNR3C1AKR1C3 | |
| SCHEMBL6201179 | 0.89 | EGLN1 (0.42) | CYP3A4LMNAMAPTNR3C1AKR1C3 | |
| SCHEMBL6199204 | 0.88 | AKR1C3 (0.47) | CYP3A4LMNANR3C1AKR1C3AKR1C4 | |
| SCHEMBL6199212 | 0.88 | AKR1C3 (0.47) | CYP3A4LMNANR3C1AKR1C3AKR1C4 | |
| SCHEMBL6196787 | 0.84 | EGLN1 (0.42) | CYP3A4LMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL6196782 | 0.84 | EGLN1 (0.42) | CYP3A4LMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL6197496 | 0.84 | EGLN1 (0.43) | CYP3A4LMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL6197485 | 0.84 | EGLN1 (0.43) | CYP3A4LMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL6786960 | 0.84 | EGLN1 (0.46) | CYP3A4LMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL6202824 | 0.83 | LMNA (0.41) | CYP3A4LMNATHRBNR3C1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |