Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863448 | 0.85 | MAPT (0.50) | L3MBTL1KMT2ATDP1POLBMAPT | |
| SCHEMBL11016938 | 0.80 | TDP1 (0.43) | L3MBTL1KMT2ATDP1POLBMAPT | |
| Hydrochloric Acid SCHEMBL27672371 | 0.78 | TDP1 (0.42) | L3MBTL1KMT2ATDP1POLBMAPT | |
| SCHEMBL377017 | 0.77 | KMT2A (0.32) | KMT2ATDP1ALDH1A1MEN1 | |
| SCHEMBL15617561 | 0.75 | KMT2A (0.45) | L3MBTL1KMT2ATDP1POLBMAPT | |
| SCHEMBL15200988 | 0.72 | LMNA (0.58) | L3MBTL1KMT2ATDP1POLBMAPT | |
| SCHEMBL13665380 | 0.72 | LMNA (0.46) | L3MBTL1KMT2ATDP1POLBMAPT | |
| 5-Nitro-2-Furoic Acid SCHEMBL1221377 | 0.71 | LMNA (0.58) | L3MBTL1KMT2ATDP1POLBLMNA | |
| SCHEMBL28692686 | 0.70 | LMNA (0.51) | L3MBTL1KMT2ATDP1POLBMAPT | |
| SCHEMBL1823686 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| EP-0683659-B1 | A METHOD FOR STIMULATING HAIR GROWTH WITH CATIONIC DERIVATIVES OF MINOXIDIL USING THERAPEUTIC IONTOPHORESIS | TULSA FORTE PHARMACY ENTPR INC (US) | 2002-08-21 | — | — | EP | claimed |
| EP-0646593-A1 | Corticoid-17,21-dicarboxylic acid ester and corticosteroid-17-carboxylic acid ester-21-carbonic, process for their production and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-05 | — | — | EP | disclosed |
| EP-0640616-A2 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |