Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 18/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640239 | 0.80 | NCF1 (0.47) | NCF1 | |
| SCHEMBL4320241 | 0.80 | NCF1 (0.47) | NCF1 | |
| SCHEMBL4320148 | 0.79 | HTR2C (0.53) | HTR2C | |
| SCHEMBL4317284 | 0.79 | HTR2C (0.53) | HTR2C | |
| SCHEMBL4308400 | 0.79 | HTR2C (0.53) | HTR2C | |
| SCHEMBL4314743 | 0.78 | HTR2C (0.44) | HTR2C | |
| SCHEMBL6200332 | 0.78 | HTR2C (0.43) | HTR2C | |
| SCHEMBL4313298 | 0.76 | HTR2C (0.39) | HTR2C | |
| SCHEMBL4316440 | 0.75 | CHRNA7 (0.44) | HTR2C | |
| SCHEMBL235730 | 0.75 | CHRNA7 (0.44) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178973-B1 | PYRAZINYL-PIPERAZINE- COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2005-12-21 | — | — | EP | claimed |