Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.44 |
| ▸ | STK4 | Q13043 | 2/20 | 0.44 |
| ▸ | STK3 | Q13188 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6200951 | 0.99 | AURKA (0.59) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6201006 | 0.95 | AURKA (0.66) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6201973 | 0.88 | AURKA (0.56) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6200264 | 0.85 | AURKA (0.64) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6200494 | 0.82 | AURKA (0.71) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6200961 | 0.82 | AURKA (0.71) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6201508 | 0.81 | AURKA (0.59) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6200887 | 0.80 | AURKA (0.57) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL6203308 | 0.78 | AURKA (0.55) | AURKAALDH1A1HPGDHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL6204384 | 0.78 | AURKA (0.44) | AURKAALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425283-B1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | US | disclosed |
| US-6767999-B2 | ANTHOCYANIC COLORANT FOR USE AS TOOL IN FOOD, COSMETIC, PHARMACEUTICAL AND TEXTILE PRODUCTION AND PROCESSING | SMIRNOV VITALY ALEKSEEVICH | 2004-07-27 | — | — | US | disclosed |
| US-6767999-B2 | ANTHOCYANIC COLORANT FOR USE AS TOOL IN FOOD, COSMETIC, PHARMACEUTICAL AND TEXTILE PRODUCTION AND PROCESSING | SMIRNOV VITALY ALEKSEEVICH | 2004-07-27 | — | — | US | disclosed |
| EP-1425283-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003018589-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-03-06 | — | — | WO | disclosed |
| US-20030036640-A1 | Anthocyantin coloring agent and method for the production thereof from organic matter | SMIRNOV VITALY ALEKSEEVICH (MD) | 2003-02-20 | — | — | US | disclosed |
| US-20030036640-A1 | Anthocyantin coloring agent and method for the production thereof from organic matter | SMIRNOV VITALY ALEKSEEVICH (MD) | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | DPYD, TPMT, TYMP | AURKA 795/4885ALDH1A1 176/4885HPGD 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.