Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.44 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205419 | 0.92 | CCNE1 (0.36) | CCNE1CDK2PKMGAANPC1 | |
| SCHEMBL6204991 | 0.86 | PKM (0.42) | CCNE1CDK2PKMGAANPC1 | |
| SCHEMBL6203391 | 0.83 | CCNE2 (0.31) | CCNE1CDK2CCNT1CCNE2CDK9 | |
| SCHEMBL6201113 | 0.81 | CDK1 (0.46) | CCNE1CDK2NPC1CCNT1CCNE2 | |
| SCHEMBL3444561 | 0.80 | CDK2 (0.50) | CCNE1CDK2PKMGAANPC1 | |
| SCHEMBL6203896 | 0.80 | CCNE2 (0.37) | CCNE1CDK2CCNT1CCNE2CDK9 | |
| SCHEMBL3446101 | 0.79 | PKM (0.46) | CCNE1CDK2PKMGAANPC1 | |
| SCHEMBL3444999 | 0.78 | PKM (0.45) | CCNE1CDK2PKMGAANPC1 | |
| SCHEMBL3445452 | 0.78 | CDK2 (0.64) | CCNE1CDK2PKMGAANPC1 | |
| SCHEMBL6205622 | 0.78 | CCNE2 (0.35) | CCNE1CDK2CCNT1CCNE2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |