Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198755 | 0.85 | POLA1 (0.57) | EGLN1ALDH1A1LMNAHTTHPGD | |
| SCHEMBL6198610 | 0.85 | EGLN1 (0.56) | EGLN1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6198915 | 0.85 | EGLN1 (0.51) | EGLN1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6198854 | 0.83 | EGLN1 (0.54) | EGLN1ALDH1A1LMNAHTTHPGD | |
| SCHEMBL6202284 | 0.83 | EGLN1 (0.54) | EGLN1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6198193 | 0.83 | EGLN1 (0.54) | EGLN1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6200839 | 0.83 | EGLN1 (0.54) | EGLN1ALDH1A1LMNAHTTHPGD | |
| SCHEMBL6219084 | 0.83 | EGLN1 (0.54) | EGLN1ALDH1A1LMNAHTTHPGD | |
| SCHEMBL6202038 | 0.83 | EGLN1 (0.54) | EGLN1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6202819 | 0.82 | L3MBTL1 (0.46) | EGLN1ALDH1A1LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |