Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860211 | 0.94 | MEN1 (0.49) | MEN1KMT2ASTSNPC1RAB9A | |
| SCHEMBL6203607 | 0.88 | NPC1 (0.47) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10830967 | 0.87 | DHFR (0.49) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL6210554 | 0.83 | MEN1 (0.51) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL11767308 | 0.83 | ELANE (0.52) | MEN1KMT2ASTSNPC1RAB9A | |
| SCHEMBL11769443 | 0.83 | MEN1 (0.48) | MEN1KMT2ASRD5A2DHFR | |
| SCHEMBL18170299 | 0.82 | NPC1 (0.44) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL6768580 | 0.82 | SRD5A2 (0.56) | MEN1KMT2AMAPTL3MBTL1KDM4E | |
| SCHEMBL5722254 | 0.82 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL225085 | 0.81 | KMT2A (0.65) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |