Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203143 | 0.76 | AVPR2 (0.59) | — | |
| SCHEMBL6203853 | 0.74 | AVPR2 (0.50) | EPHX2NR1H4ALDH1A1P2RX7CYP2C9 | |
| SCHEMBL12231188 | 0.74 | EPHX2 (0.50) | EPHX2NR1H4ALDH1A1LMNAMAPK1 | |
| SCHEMBL6202917 | 0.72 | AVPR2 (0.48) | EPHX2NR1H4ALDH1A1P2RX7CYP2C9 | |
| SCHEMBL6202207 | 0.72 | AVPR2 (0.48) | EPHX2NR1H4ALDH1A1P2RX7CYP2C9 | |
| SCHEMBL6202923 | 0.71 | EPHX2 (0.37) | EPHX2NR1H4ALDH1A1LMNAMAPK1 | |
| SCHEMBL1346036 | 0.68 | EPHX2 (0.64) | EPHX2NR1H4ALDH1A1LMNAMAPK1 | |
| SCHEMBL13780329 | 0.67 | EPHX2 (0.50) | EPHX2NR1H4ALDH1A1LMNAMAPK1 | |
| SCHEMBL25930148 | 0.67 | CTSC (0.36) | MAPK1CTSC | |
| SCHEMBL7270417 | 0.67 | CTSC (0.36) | MAPK1CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399436-B1 | OXYTOCIN AGONISTS | FERRING BV (NL) | 2005-03-16 | — | — | EP | disclosed |
| EP-1399436-A2 | OXYTOCIN AGONISTS | Ferring BV (NL) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000692-A2 | OXYTOCIN AGONISTS | FERRING BV (NL) | 2003-01-03 | — | — | WO | disclosed |