Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950040 | 0.94 | RAB9A (0.88) | RAB9ANPC1L3MBTL1MAPTCNR1 | |
| SCHEMBL6011931 | 0.86 | RAB9A (0.75) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2051943 | 0.86 | RAB9A (0.75) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7820941 | 0.85 | RAB9A (0.73) | RAB9ANPC1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL29986829 | 0.84 | RAB9A (0.73) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29017606 | 0.84 | RAB9A (0.73) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28172864 | 0.84 | RAB9A (0.73) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11622188 | 0.84 | RAB9A (0.73) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL30333799 | 0.84 | RAB9A (0.73) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| Bromide SCHEMBL28156394 | 0.84 | RAB9A (0.73) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |