Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYAB | P02511 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | CRYAA | P02489 | 1/20 | 0.69 |
| ▸ | PTGES | O14684 | 2/20 | 0.64 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lanosterol SCHEMBL16994483 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL145834 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL14536063 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL1696473 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL19194030 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL2154745 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL145835 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL14360758 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL21348006 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL14240642 | 0.89 | MAPT (1.00) | CRYABMAPTUSP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019644-A1 | PRODUCING 1ALPHA, 25 -DIHYDROXYVITAMIN D3 IN PLANT CELLS AND PLANTS AND METHODS FOR UP-REGULATING CORRESPONDING METABOLIC PATHWAYS | HERBONIS AG (CH) | 2012-02-16 | — | — | WO | claimed |
| WO-2012019644-A1 | PRODUCING 1ALPHA, 25 -DIHYDROXYVITAMIN D3 IN PLANT CELLS AND PLANTS AND METHODS FOR UP-REGULATING CORRESPONDING METABOLIC PATHWAYS | HERBONIS AG (CH) | 2012-02-16 | — | — | WO | disclosed |