Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.65 |
| ▸ | PPARG | P37231 | 12/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031028 | 0.84 | PPARA (0.69) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL4027996 | 0.83 | PPARG (0.71) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL6204165 | 0.83 | PPARA (0.78) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL4744872 | 0.81 | PPARA (0.64) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL4029074 | 0.81 | PPARG (0.68) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL4025628 | 0.80 | PPARA (0.71) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL4031030 | 0.80 | PPARA (0.74) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL4025490 | 0.80 | PPARA (0.70) | PPARAPPARGPPARDFFAR1KDM4E | |
| SCHEMBL13633880 | 0.79 | PPARA (0.86) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL4025234 | 0.79 | PPARA (1.00) | PPARAPPARGPPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD. (IN) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004046119-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2004-06-03 | — | — | WO | disclosed |