Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 6/20 | 0.65 |
| ▸ | RORC | P51449 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413421 | 0.86 | ALDH1A1 (0.77) | ALDH1A1GAAHPGDTSHRMEN1 | |
| SCHEMBL3988276 | 0.86 | ALDH1A1 (0.97) | ALDH1A1GAAHPGDTSHRESR2 | |
| SCHEMBL6263808 | 0.84 | CNR2 (0.73) | ALDH1A1GAAHPGDTSHRESR2 | |
| SCHEMBL6202090 | 0.83 | ALDH1A1 (0.79) | ALDH1A1GAAHPGDTSHRMEN1 | |
| SCHEMBL6203815 | 0.83 | ALDH1A1 (0.79) | ALDH1A1GAAHPGDTSHRMEN1 | |
| SCHEMBL6203540 | 0.82 | ALDH1A1 (0.80) | ALDH1A1GAAHPGDTSHRMEN1 | |
| SCHEMBL6203156 | 0.81 | ALDH1A1 (0.82) | ALDH1A1GAAHPGDTSHRMEN1 | |
| SCHEMBL6200055 | 0.81 | ALDH1A1 (0.82) | ALDH1A1GAAHPGDTSHRMEN1 | |
| SCHEMBL8288576 | 0.81 | ALDH1A1 (0.71) | ALDH1A1GAAHPGDTSHRESR2 | |
| SCHEMBL6205045 | 0.81 | ESR2 (0.68) | ALDH1A1GAAHPGDTSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509514-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003101979-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2003-12-11 | — | — | WO | claimed |