Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201109 | 0.93 | MCL1 (0.47) | MCL1KDM4EHPGDEGLN1POLB | |
| SCHEMBL6200333 | 0.90 | MCL1 (0.48) | MCL1EGLN1LMNAMAPTKMT2A | |
| SCHEMBL6201656 | 0.90 | MCL1 (0.44) | MCL1EGLN1LMNAMAPTKMT2A | |
| SCHEMBL6199253 | 0.89 | MCL1 (0.44) | MCL1HPGDEGLN1LMNAKMT2A | |
| SCHEMBL6202136 | 0.88 | SMN1; SMN2 (0.45) | MCL1KDM4EHPGDEGLN1POLB | |
| SCHEMBL6199190 | 0.87 | MCL1 (0.47) | MCL1KDM4EEGLN1LMNAALDH1A1 | |
| SCHEMBL6198666 | 0.87 | MCL1 (0.42) | MCL1EGLN1LMNAMAPTKMT2A | |
| SCHEMBL6199074 | 0.87 | MCL1 (0.44) | MCL1HPGDEGLN1LMNAALDH1A1 | |
| SCHEMBL6202650 | 0.87 | MCL1 (0.39) | MCL1EGLN1LMNAMAPTKMT2A | |
| SCHEMBL6201979 | 0.87 | MCL1 (0.52) | MCL1KDM4EHPGDEGLN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |