Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203567 | 0.93 | MCL1 (0.43) | MCL1SMN1; SMN2POLBEGLN1HPGD | |
| SCHEMBL6201979 | 0.91 | MCL1 (0.52) | MCL1POLBEGLN1HPGDKDM4E | |
| SCHEMBL6197449 | 0.88 | MCL1 (0.48) | MCL1EGLN1HPGDKDM4ELMNA | |
| SCHEMBL6199456 | 0.88 | PPARG (0.45) | MCL1EGLN1KDM4ELMNATUBB | |
| SCHEMBL6199253 | 0.87 | MCL1 (0.44) | MCL1EGLN1HPGDLMNATUBB | |
| SCHEMBL6198214 | 0.87 | SMN1; SMN2 (0.51) | MCL1SMN1; SMN2POLBEGLN1HPGD | |
| SCHEMBL6202730 | 0.87 | ALDH1A1 (0.47) | MCL1SMN1; SMN2POLBEGLN1KDM4E | |
| SCHEMBL6198581 | 0.86 | MCL1 (0.48) | MCL1EGLN1HPGDKDM4ELMNA | |
| SCHEMBL6200211 | 0.86 | MCL1 (0.48) | MCL1EGLN1HPGDKDM4ELMNA | |
| SCHEMBL6201217 | 0.86 | MCL1 (0.47) | MCL1EGLN1LMNATUBBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |