⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453038 | 0.79 | — | — | |
| SCHEMBL6207561 | 0.77 | — | — | |
| SCHEMBL5664420 | 0.77 | — | — | |
| SCHEMBL3736221 | 0.75 | GABRP (0.49) | — | |
| SCHEMBL28116640 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL5504193 | 0.74 | — | — | |
| SCHEMBL11004269 | 0.74 | PRSS1 (0.33) | — | |
| SCHEMBL27606447 | 0.74 | ESR1 (0.52) | — | |
| SCHEMBL21550330 | 0.73 | — | — | |
| SCHEMBL147803 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085029-A | Enzyme-responsive controlled-release antibiotic prodrug, and preparation method and application thereof | 国家纳米科学中心 | 2024-05-28 | — | — | CN | claimed |
| CN-118085029-A | Enzyme-responsive controlled-release antibiotic prodrug, and preparation method and application thereof | 国家纳米科学中心 | 2024-05-28 | — | — | CN | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |