Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691596 | 0.84 | IDO1 (0.37) | IDO1CA12CA1CA2CA4 | |
| SCHEMBL456067 | 0.82 | TAAR1 (0.37) | IDO1CA12CA1CA2CA4 | |
| SCHEMBL6436641 | 0.80 | MCL1 (0.33) | CA12CA1CA2CA4CA7 | |
| SCHEMBL9409469 | 0.80 | TAAR1 (0.37) | IDO1CA12CA1CA2CA4 | |
| SCHEMBL2480627 | 0.80 | PDE4A (0.44) | CA12CA1CA2CA4CA7 | |
| SCHEMBL8475524 | 0.78 | HMGCR (0.43) | — | |
| SCHEMBL18705900 | 0.78 | SLC6A4 (0.42) | — | |
| SCHEMBL11859769 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL8480844 | 0.77 | TAAR1 (0.35) | — | |
| SCHEMBL18706153 | 0.77 | SLC6A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |