Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 15/20 | 0.37 |
| ▸ | CDK2 | P24941 | 15/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 12/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CCNH | P51946 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PDE6C | P51160 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203399 | 0.81 | KMT2A (0.42) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL3446389 | 0.78 | CDK2 (0.43) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL3444367 | 0.77 | CDK2 (0.51) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL3444363 | 0.77 | CDK2 (0.51) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL3445671 | 0.77 | CDK2 (0.40) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL3445759 | 0.77 | CDK2 (0.54) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL6204218 | 0.76 | CCNE2 (0.30) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL6205469 | 0.75 | — | — | |
| SCHEMBL3444611 | 0.73 | CCNE1 (0.56) | CCNE1CDK2CCNE2CDK5CDK1 | |
| SCHEMBL3445371 | 0.71 | CLK1 (0.48) | CCNE1CDK2CCNE2CDK5CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |