Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.33 |
| ▸ | CDK2 | P24941 | 7/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.33 |
| ▸ | CDK7 | P50613 | 4/20 | 0.33 |
| ▸ | CCNH | P51946 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.32 |
| ▸ | CDK9 | P50750 | 5/20 | 0.32 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446389 | 0.83 | CDK2 (0.43) | CCNE1CDK2CDK5CDK5R1CDK7 | |
| SCHEMBL3445671 | 0.83 | CDK2 (0.40) | CCNE1CDK2CDK5CDK5R1CDK7 | |
| SCHEMBL3444367 | 0.81 | CDK2 (0.51) | KMT2AALDH1A1CCNE1CDK2CDK5 | |
| SCHEMBL3444363 | 0.81 | CDK2 (0.51) | KMT2AALDH1A1CCNE1CDK2CDK5 | |
| SCHEMBL6204366 | 0.81 | CCNE1 (0.37) | CCNE1CDK2CDK5CDK5R1CDK7 | |
| SCHEMBL3445759 | 0.80 | CDK2 (0.54) | ALDH1A1LMNASMN1; SMN2CCNE1CDK2 | |
| SCHEMBL3444611 | 0.78 | CCNE1 (0.56) | CCNE1CDK2CDK5CDK5R1CDK7 | |
| SCHEMBL3445371 | 0.77 | CLK1 (0.48) | CCNE1CDK2CDK5CDK5R1CDK7 | |
| SCHEMBL6226169 | 0.76 | KMT2A (0.56) | KMT2AALDH1A1LMNASMN1; SMN2CDK2 | |
| SCHEMBL6203983 | 0.76 | KMT2A (0.42) | KMT2AALDH1A1LMNASMN1; SMN2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |