Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603896 | 0.83 | CES2 (0.55) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL15050109 | 0.83 | SLC6A2 (0.46) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL15050110 | 0.83 | SLC6A2 (0.46) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL15050108 | 0.83 | SLC6A2 (0.46) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL6204441 | 0.81 | CES2 (0.47) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL15714990 | 0.81 | SLC6A2 (0.44) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL17660052 | 0.80 | CES2 (0.49) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL16412814 | 0.80 | CES2 (0.49) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL16419139 | 0.80 | CES2 (0.49) | CES2CES1SLC6A2SLC6A4HDAC4 | |
| SCHEMBL30988818 | 0.80 | CES2 (0.49) | CES2CES1SLC6A2SLC6A4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |