Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | AGXT | P21549 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224557 | 0.85 | TAAR1 (0.73) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL2427142 | 0.84 | TAAR1 (0.71) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL9071087 | 0.84 | TAAR1 (0.71) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL29365903 | 0.84 | TAAR1 (0.71) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL11333474 | 0.84 | TAAR1 (0.71) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL7450409 | 0.83 | TAAR1 (0.70) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL27302315 | 0.82 | TAAR1 (0.64) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL3179539 | 0.81 | TAAR1 (0.62) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL7510495 | 0.81 | TAAR1 (0.62) | TAAR1IDO1AGXTADRB2CHRM2 | |
| SCHEMBL7510484 | 0.81 | TAAR1 (0.62) | TAAR1IDO1AGXTADRB2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |
| US-4066648-A | ANTIDEPRESSANTS, ANALGESICS, DIURETICS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS, VASODIALATORS, HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-03 | — | — | US | disclosed |