⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL4973856 | 0.82 | — | — | |
| Ether SCHEMBL11882966 | 0.82 | — | — | |
| Ether SCHEMBL9788714 | 0.82 | — | — | |
| Ether SCHEMBL9248674 | 0.82 | ALDH1A1 (0.47) | — | |
| Ether SCHEMBL21406 | 0.82 | ALDH1A1 (0.47) | — | |
| Ether SCHEMBL9248046 | 0.82 | ALDH1A1 (0.47) | — | |
| Ether SCHEMBL6 | 0.82 | — | — | |
| Ether SCHEMBL8160191 | 0.82 | ALDH1A1 (0.47) | — | |
| Ether SCHEMBL9333712 | 0.78 | ALDH1A1 (0.39) | — | |
| Ether SCHEMBL9567021 | 0.78 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108285455-B | 4 beta-amino substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2022-02-08 | — | — | CN | claimed |
| CN-107400060-B | A kind of synthetic method of the chloro- 6- bromaniline of 2- | 大连理工大学 | 2019-04-05 | — | — | CN | claimed |
| EP-1960344-A1 | ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID | CHEMTURA CORPORATION (US) | 2008-08-27 | — | — | EP | claimed |
| WO-2007070264-A1 | ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID | CHEMTURA CORPORATION (US) | 2007-06-21 | — | — | WO | claimed |
| US-7145038-B1 | Alkylation of a diphenylamine compound in ionic liquid | CHEMTURA CORPORATION (US) | 2006-12-05 | — | — | US | claimed |
| CN-1155167-A | Polythiophene-conductive-fiber composite film and making method and usage thereof | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 1997-07-23 | — | — | CN | claimed |
| CN-116326703-A | Phospholipid emulsion beverage containing sea buckthorn seed oil and preparation method thereof | 沈阳信康药物研究有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114479052-A | Photocuring diluent and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-108285455-B | 4 beta-amino substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2022-02-08 | — | — | CN | disclosed |
| CN-113603840-A | Preparation method of antirust slow-release polycarboxylic acid superplasticizer | 抚顺东科精细化工有限公司 | 2021-11-05 | — | — | CN | disclosed |
| US-20210252156-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERON THERAPEUTICS INC (US) | 2021-08-19 | — | — | US | disclosed |
| EP-3834817-A1 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | Heron Therapeutics, Inc. (US) | 2021-06-16 | — | — | EP | disclosed |
| US-20200405866-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERON THERAPEUTICS, INC. | 2020-12-31 | — | — | US | disclosed |
| US-4093709-A | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) | ALZA CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4066747-A | Polymeric orthoesters housing beneficial drug for controlled release therefrom | ALZA CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4055593-A | OXYTOCICS, ANTIULCER, DECONGESTANTS, ANTICLUMPING, MUSCLE RELAXANT, ANTISECRETORY, BLOOD PRESSURE, LIPOLYSIS | ALZA CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4045577-A | 15-PROPIONYLOXY-9-OXO-5,13 PROSTADIENOIC ACID, ANTIHYPERTENSIVE AGENTS | ALZA CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3994828-A | Nonabsorbable antioxidant | DYNAPOL CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3989768-A | Chemically joined phase separated thermoplastic graft copolymers | CPC INTERNATIONAL INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3954803-A | Dilactone chromogenic compounds and preparation thereof | CHAMPION INTERNATIONAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |