Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | BCR | P11274 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22964601 | 0.72 | ABL1 (0.37) | ABL1BCRMEN1KMT2ARPS6KA5 | |
| SCHEMBL25128598 | 0.71 | MEN1 (0.39) | ABL1BCRMEN1KMT2ARPS6KA5 | |
| SCHEMBL5149760 | 0.71 | ABL1 (0.33) | ABL1BCR | |
| SCHEMBL4071074 | 0.69 | KMT2A (0.37) | ABL1BCRKMT2A | |
| SCHEMBL3139273 | 0.68 | MEN1 (0.36) | ABL1BCRMEN1KMT2ASTK17B | |
| SCHEMBL6210264 | 0.67 | SLC6A2 (0.34) | ABL1BCRMEN1KMT2A | |
| SCHEMBL6212769 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL3447093 | 0.67 | STK17B (0.36) | ABL1BCRMEN1KMT2ASTK17B | |
| SCHEMBL6215293 | 0.66 | MAPT (0.33) | — | |
| SCHEMBL5151737 | 0.66 | STK17A (0.50) | MEN1KMT2ASTK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530574-A1 | MACROCYCLIC PYRIMIDINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004026881-A1 | MACROCYCLIC PYRIMIDINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-01 | — | — | WO | disclosed |