Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABL2 | P42684 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12596982 | 0.78 | ADH1A (0.49) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL12596985 | 0.78 | ADH1A (0.49) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL18089333 | 0.78 | ADH1A (0.65) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL29416531 | 0.78 | ADH1A (0.65) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL1903631 | 0.78 | ADH1A (0.65) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL16781599 | 0.78 | ADH1A (0.65) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL1899623 | 0.78 | ADH1A (0.65) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6207802 | 0.77 | ADH1A (0.35) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL16847519 | 0.77 | ADH1A (0.48) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL16487040 | 0.77 | ADH1A (0.50) | ADH1AKITFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-B1 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2005-11-23 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |