Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 18/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994154 | 0.88 | SLC6A4 (0.62) | SLC6A4SLC6A2 | |
| SCHEMBL5992943 | 0.78 | SLC6A4 (0.62) | SLC6A4SLC6A2HTR2A | |
| SCHEMBL5997831 | 0.74 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5995931 | 0.73 | SLC6A4 (0.51) | SLC6A4SLC6A2 | |
| SCHEMBL5997164 | 0.72 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3 | |
| Cadaverine Tartrate SCHEMBL5993760 | 0.71 | SLC6A4 (0.91) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5994452 | 0.70 | EPHX2 (0.48) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5997010 | 0.70 | SLC6A4 (0.75) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16269692 | 0.70 | EPHX2 (0.53) | SLC6A4SLC6A2HTR2A | |
| SCHEMBL6183532 | 0.69 | SLC6A2 (0.60) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569905-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052858-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |