Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203958 | 0.93 | CCR2 (0.55) | CCR2 | |
| SCHEMBL4848338 | 0.93 | CCR2 (0.59) | CCR2 | |
| SCHEMBL4845980 | 0.93 | CCR2 (0.59) | CCR2 | |
| SCHEMBL4842670 | 0.92 | CCR2 (0.69) | CCR2 | |
| SCHEMBL4840102 | 0.92 | CCR2 (0.60) | CCR2 | |
| SCHEMBL4846565 | 0.90 | CCR2 (0.61) | CCR2 | |
| SCHEMBL4847930 | 0.89 | CCR2 (0.55) | CCR2 | |
| SCHEMBL4845530 | 0.89 | CCR2 (0.57) | CCR2 | |
| SCHEMBL4845489 | 0.89 | CCR2 (0.58) | CCR2 | |
| SCHEMBL27569079 | 0.89 | CCR2 (0.57) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |