Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068720 | 0.85 | SMN1; SMN2 (0.60) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL22824153 | 0.83 | CFTR (0.46) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL21064696 | 0.83 | CFTR (0.46) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL20012923 | 0.83 | CFTR (0.46) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL2608570 | 0.81 | SMN1; SMN2 (0.51) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL7707812 | 0.79 | SMN1; SMN2 (0.42) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL11066568 | 0.79 | TBXAS1 (0.49) | — | |
| SCHEMBL6631615 | 0.78 | CFTR (0.52) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL29852317 | 0.76 | SMN1; SMN2 (0.50) | SLC6A2SLC6A4CFTRSLC6A3GOPC | |
| SCHEMBL28134029 | 0.76 | SMN1; SMN2 (0.50) | SLC6A2SLC6A4CFTRSLC6A3GOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102892759-B | Nitrogen-containing heterocyclic compound having kynurenine production inhibitory action | KYOWA HAKKO KIRIN CO LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-102892759-A | Nitrogen-containing heterocyclic compound having kynurenine production inhibitory action | KYOWA HAKKO KIRIN CO LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-1668601-A | N-substituted tricyclic 3-aminopyrazoles as PDFG receptor inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2005-09-14 | — | — | CN | disclosed |
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |
| US-4971984-A | Cardiovascular disorders, hypotensive agints | BEEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |