Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190882 | 0.81 | AKR1B1 (0.38) | CA2 | |
| SCHEMBL28475451 | 0.58 | — | — | |
| SCHEMBL693912 | 0.58 | — | — | |
| SCHEMBL9653572 | 0.57 | — | — | |
| SCHEMBL25676 | 0.56 | CES1 (0.64) | CA2 | |
| SCHEMBL21184718 | 0.56 | CA2 (0.56) | CA2HTT | |
| SCHEMBL11290860 | 0.56 | CA2 (0.80) | CA2 | |
| Hydrochloric Acid SCHEMBL1621316 | 0.55 | CES1 (0.61) | CA2 | |
| SCHEMBL10339219 | 0.55 | CA2 (0.54) | CA2 | |
| Hydrochloric Acid SCHEMBL3651517 | 0.55 | CES1 (0.61) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567525-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS AND THEIR USE AS FATTY ACID OXIDATION INHIBITORS | CV THERAPEUTICS, INC. (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004052887-A2 | SUBSTITUTED PIPERAZINE COMPOUNDS AND THEIR USE AS FATTY ACID OXIDATION INHIBITORS | CV THERAPEUTICS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |