SCHEMBL6205437

SCHEMBL6205437

CC(=O)On1nnc(COc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 5/20 0.31
▸ PPOX P50336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6207133 0.93 — —
SCHEMBL2836052 0.88 PDE7A (0.38) DHODHPPOX
SCHEMBL2833156 0.86 DOT1L (0.33) DHODH
SCHEMBL2835867 0.85 PPOX (0.31) PPOX
SCHEMBL6226436 0.84 DHODH (0.30) DHODH
SCHEMBL6206905 0.83 DHODH (0.30) DHODH
SCHEMBL6205845 0.83 — —
SCHEMBL1573521 0.81 DHODH (0.30) DHODH
SCHEMBL2840891 0.81 PDE7A (0.37) —
SCHEMBL10577248 0.81 HDAC1 (0.34) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585737-A2 URACILS HAVING A HERBICIDAL ACTIVITY Isagro Ricerca S.r.l. (IT) 2005-10-19 — — EP claimed
WO-2004056785-A2 URACILS HAVING A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2004-07-08 — — WO claimed
EP-1585737-A2 URACILS HAVING A HERBICIDAL ACTIVITY Isagro Ricerca S.r.l. (IT) 2005-10-19 — — EP disclosed
WO-2004056785-A2 URACILS HAVING A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2004-07-08 — — WO disclosed
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