SCHEMBL6205484

SCHEMBL6205484

Fc1ccc(F)c(-c2cccs2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 1/20 0.54
MAPT P10636 6/20 0.47
GABRA1 P14867 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
KDM4E B2RXH2 3/20 0.42
ERN1 O75460 1/20 0.41
RAB9A P51151 6/20 0.41
NPC1 O15118 4/20 0.41
ATM Q13315 2/20 0.41
RXFP1 Q9HBX9 2/20 0.40
PTGER2 P43116 1/20 0.40
KIF11 P52732 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27965042 0.86 MAPT (0.49) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL4207045 0.84 MAPT (0.47) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL2782222 0.83 NPC1 (0.46) TNFRSF1AMAPTKDM4EERN1RAB9A
SCHEMBL21052177 0.81 KCNH2 (0.50) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL27572736 0.81 MAPT (0.45) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL6764756 0.81 MAPT (0.45) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL3530209 0.81 NPC1 (0.46) TNFRSF1AMAPTKDM4EERN1RAB9A
SCHEMBL6764775 0.78 MAPT (0.46) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL11707032 0.77 MAPT (0.45) TNFRSF1AMAPTGABRA1GABRG2GABRB3
SCHEMBL155112 0.77 LTA4H (0.47) TNFRSF1AMAPTKDM4EERN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999023711-A9 AN ELECTROCHEMICAL STORAGE CELL CONTAINING AT LEAST ONE ELECTRODE FORMULATED FROM A PHENYLENE-THIENYL BASED POLYMER UNIV JOHNS HOPKINS (US) 1999-08-12 WO claimed
WO-1999023711-A1 AN ELECTROCHEMICAL STORAGE CELL CONTAINING AT LEAST ONE ELECTRODE FORMULATED FROM A PHENYLENE-THIENYL BASED POLYMER THE JOHNS HOPKINS UNIVERSITY (US) 1999-05-14 WO claimed
CN-104168958-B Diaryl sulfonamides useful for the treatment of inflammation and cancer 坎塞拉有限公司 2017-12-01 CN disclosed
CN-104168958-A Diaryl sulfonamides useful for the treatment of inflammation and cancer KANCERA AB 2014-11-26 CN disclosed
EP-1551847-A1 3,4-ALKYLENEDIOXYTHIOPHENE COMPOUNDS AND POLYMERS THEREOF Agfa-Gevaert (BE) 2005-07-13 EP disclosed
WO-2004031192-A1 3,4-ALKYLENEDIOXYTHIOPHENE COMPOUNDS AND POLYMERS THEREOF AGFA-GEVAERT (BE) 2004-04-15 WO disclosed
WO-2000041255-A1 METHOD FOR ELECTROCHEMICAL CONDITIONING POLYMERIC ELECTRODES JOHNS HOPKINS UNIVERSITY (US) 2000-07-13 WO disclosed
WO-1999023711-A9 AN ELECTROCHEMICAL STORAGE CELL CONTAINING AT LEAST ONE ELECTRODE FORMULATED FROM A PHENYLENE-THIENYL BASED POLYMER UNIV JOHNS HOPKINS (US) 1999-08-12 WO disclosed
WO-1999023711-A1 AN ELECTROCHEMICAL STORAGE CELL CONTAINING AT LEAST ONE ELECTRODE FORMULATED FROM A PHENYLENE-THIENYL BASED POLYMER THE JOHNS HOPKINS UNIVERSITY (US) 1999-05-14 WO disclosed