Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525518 | 1.00 | KDM4E (0.49) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL12827006 | 0.83 | KDM4E (0.51) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL4661763 | 0.82 | KDM4E (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL518792 | 0.79 | KDM4E (0.47) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL31070307 | 0.78 | KDM4E (0.53) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL9577471 | 0.77 | KDM4E (0.49) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL14694209 | 0.77 | AOC3 (0.56) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL15641062 | 0.76 | IDO1 (0.48) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL5692312 | 0.75 | AHR (0.56) | KDM4EDAOMAPTHPGDSRD5A2 | |
| Indole-2-Carboxylic Acid SCHEMBL27785397 | 0.75 | KDM4E (0.80) | KDM4EDAOMAPTHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114134186-B | Method for synthesizing 5-hydroxy beta-indolylalanine by using glucose as substrate biological method | 河北维达康生物科技有限公司 | 2025-04-22 | — | — | CN | disclosed |
| EP-1313736-B1 | CONDENSED PYRAZINDIONE DERIVATIVES AS INHIBITORS OF PDE5 | LILLY ICOS LLC (US) | 2005-07-27 | — | — | EP | disclosed |
| US-6903099-B2 | Condensed pyrazindione derivatives | LILLY ICOS LLC (US) | 2005-06-07 | — | — | US | disclosed |
| US-20030181457-A1 | Chemical compounds | LILLY ICOS LLC | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181457-A1 | Chemical compounds | ABCG2, SDHA, CYP11B1 | KDM4E 4466/4885DAO 1427/4885MAPT 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.